The official  flagship store: products are patented.  Counterfeiting will be prosecuted.Dr. Donna H. Ryan (Click to learn more about Dr. Donna H. Ryan)

The TLOPA® 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 𝐍𝐚𝐧𝐨 𝐌𝐢𝐜𝐫𝐨𝐧𝐞𝐞𝐝𝐥𝐞 𝐏𝐚𝐭𝐜𝐡 has been meticulously developed by The Obesity Society. Designed by a team of leading experts in obesity management, this cutting-edge product was created following years of in-depth research and a comprehensive understanding of the mechanisms involved in weight loss and obesity control. Its unique formulation is designed to effectively promote weight loss, maintain stable blood sugar levels, and enhance metabolic balance, while incorporating TLOPA®3000 to deliver significant lifting and firming effects, helping users improve body shape and skin condition more comprehensively, thus supporting them in achieving their health goals.

This nano microneedle patch utilizes advanced SMGT-GLP-1 technology, delivering active ingredients precisely to the deeper layers of the skin. It scientifically regulates insulin secretion, suppresses glucagon, delays gastric emptying, and assists in controlling blood sugar levels, thereby promoting healthy fat reduction and optimizing overall health management. Meanwhile, TLOPA® 3000 stimulates skin regeneration, enhancing skin firmness, allowing users to maintain tight and smooth skin while losing weight.

Let’s take a look at what makes the TLOPA® SMGT-GLP-1 Nano Microneedle Patch so special.

The Nano Microneedle Patch contains SMGT-GLP-1 in each patch. It works by mimicking the action of Glucagon-like Peptide-1 (GLP-1), promoting insulin secretion, inhibiting glucagon secretion, and delaying gastric emptying, which helps control blood sugar levels and aids in weight loss.

To enhance the overall slimming and firming effect, the patch is also infused with Matrixyl 3000 — a powerful peptide complex known for its ability to stimulate collagen production, visibly tighten skin, and reduce the appearance of fine lines and sagging often associated with rapid weight loss.

Typically, SMGT-GLP-1 is administered via injection, providing fast results in a short period. However, the effects do not last long, and it may lead to stress reactions, requiring multiple injections in a short time, which is time-consuming and expensive.

The TLOPA® SMGT-GLP-1 Nano Microneedle Patch offers a long-lasting, slow release of the medication, ensuring a stable effect over 24 hours without causing any discomfort. With the same dosage and price, it can maintain up to 20 times longer-lasting effects (similar to the difference between an IV drip and a single injection).

Let’s take a look at some of the cases from our users

“I suffer from both obesity and diabetes, and I had been receiving SMGT-GLP-1 (also known as semaglutide) treatments at the hospital. You might wonder why I suddenly switched to the TLOPA®Nano Microneedle Patch. Honestly, semaglutide is an excellent treatment — shortly after each injection, my appetite decreased, I lost weight quickly, and my blood sugar levels dropped.

But sticking to regular injections isn’t easy. On injection days, I’d always find excuses to skip — the cost, the hunger, scheduling conflicts, or even something as simple as bad weather would stop me. Over time, this inconsistency affected the results.

That’s why the TLOPA® Nano Microneedle Patch is perfect for someone like me who struggles with consistency. I can apply it easily at home, and the slow-release formula works for a full 24 hours, helping me control my appetite steadily. Plus, it’s very affordable — it makes SMGT-GLP-1 accessible for anyone looking to lose weight and manage their blood sugar.

What surprised me even more is that TLOPA® is different from other fast weight-loss products. My skin didn’t sag after losing weight — instead, it became noticeably firmer and more toned during the process.“

“For all these years, I’ve really been “fighting” with my diet. As a diabetic, there are so many things I can’t eat—just a little slip-up and my blood sugar spikes. What’s even more frustrating is that despite all my efforts, my weight hasn’t changed at all, and my blood sugar is still all over the place. My doctor even told me that some foods might help with weight loss, but they don’t do anything for blood sugar control, which was so disheartening.

I’ve also tried other weight loss products before—yes, I lost a bit of weight, but my skin ended up loose and saggy, and I looked more tired and drained. But the TLOPA® Nano Microneedle Patch is different. It contains Matrixyl 3000, and the firming effect is really noticeable—my skin not only didn’t loosen, it actually feels firmer! I’ve used it consistently for 84 days, and the results are amazing: I’ve lost several kilos, my blood sugar is back to normal, and I look younger. My friends have even commented on how much more vibrant I look! It’s so easy to use—just once a week—and I can eat whatever I want, and it helps automatically control my portion sizes. It’s honestly incredible!

If I hadn’t seen the promotion for this product by chance at the pharmacy, I might have never discovered such an amazing gem.”

I’m 37 years old, and after having my second child, my belly turned into the typical “mommy belly” – loose and wrinkled. I felt terrible and didn’t even want to exercise because my belly would jiggle with every step. I tried cocoa butter and massages for two months, but nothing really changed. My doctor suggested surgery, but I didn’t want any scars or the high costs. So, my husband ordered the TLOPA® Nano Microneedle Patch with SMGT-GLP-1 and Matrixyl 3000 for me. Not only does it help with weight loss, but it also tightens my skin, and it feels amazing. I use it every day, and by the fifth day, I could feel my skin tightening, and I noticed a significant weight drop. After two weeks, my belly was completely back to normal – no wrinkles, no sagging, just firm like when I was 20. I’m planning to get some for my 60-year-old mom next because I believe it will work wonders for her aging arms too.
It wasn’t until I started having foot problems that I realized how much high blood sugar levels were affecting my daily life. It was then that I decided to try this TLOPA® Drops. Not only have my blood sugar levels stabilized, but the good circulation supports the proper healing of my feet, which I might otherwise have amputated.

 Yes, you read the feedback correctly! 

𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏, with its unique mechanism of action, has already achieved significant results in diabetes treatment and weight management!

𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 is a multi-functional treatment solution that primarily helps with weight loss by suppressing appetite and delaying gastric emptying, promoting fat burning. In the treatment of type 2 diabetes, it enhances insulin secretion and inhibits glucagon release, effectively controlling blood sugar levels and improving insulin sensitivity. Additionally, 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 offers cardiovascular protection by reducing the risk of heart disease, improving lipid profiles, and providing anti-inflammatory effects, further protecting vascular health. Therefore, it demonstrates significant efficacy in weight loss, blood sugar control, and cardiovascular protection, making it an important treatment option for type 2 diabetes patients and individuals managing their weight.

 Next-generation pain-free injection Nano Microneedle Patch. 

Each needle is 0.27mm long, just 1/7th the thickness of a hair, and is made from dissolvable medication. These micro-needles are precision-engineered using cutting-edge manufacturing techniques to ensure a seamless, pain-free experience while effectively delivering the active ingredients directly into the skin.

Recommended by endocrinologists

“Change needs to start from within.” – Dr. Ralph DeFronzo

Are you still hesitating?

TLOPA® SMGT-GLP-1 Nano Microneedle Patch has been certified by multiple national authorities.

Hurry up and give it a try! 2,250,000 people have already made a change!

Check out more of our customers’ satisfaction feedback!

“I had never used 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 treatment before, so before purchasing TLOPA® , I did a lot of research and read through several case studies. I confirmed that 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 is a great solution for weight loss. Out of all the options, the TLOPA® 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 𝐍𝐚𝐧𝐨 𝐌𝐢𝐜𝐫𝐨𝐧𝐞𝐞𝐝𝐥𝐞 𝐏𝐚𝐭𝐜𝐡 turned out to be the best choice. As I expected, during the first two weeks of use, I didn’t experience any discomfort. The results were very consistent and gradual. It helped me slowly control my appetite, and I noticed that my metabolism sped up significantly. My digestion improved, and the feeling of fullness lasted longer. After using about 3 boxes over 9 weeks, I went from 180 lbs to 128 lbs. The results came even faster than what I read online about people getting 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 injections at medical facilities! That’s because TLOPA®  has higher efficacy and better adherence to the plan. I honestly think everyone should give the 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 Microneedle Patch a try—it’s a great new treatment option.”

“I’m thrilled to have been invited by TLOPA®  to visit their headquarters. It all started when I called their official line and said, ‘I wasn’t fully convinced by your product.’ They generously invited me to visit their company and offered a trial for one course of treatment. After two weeks of use, I called them back and told them, ‘I am now absolutely convinced that your product works, and I’ll continue with it!’ In just three months, I was able to reach my ideal weight of 136 lbs. It was almost effortless. Nothing proves the truth like real results—those exaggerated claims were nothing compared to the actual experience! I’m also excited to have my experience shared as part of the company’s case studies. So, if you still have doubts, trust me—just try using two boxes, and you’ll see noticeable changes!”

What are the frequently asked questions about using the TLOPA® 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 𝐍𝐚𝐧𝐨 𝐌𝐢𝐜𝐫𝐨𝐧𝐞𝐞𝐝𝐥𝐞 𝐏𝐚𝐭𝐜𝐡?

1.When will I see results?

Generally, you may notice initial effects about 2 weeks after use, but the best results typically appear after completing 2-3 treatment cycles.

2.How long should it be applied each time?

Remove the patch after at least 4 hours.  (If using the patch at night, remove it the next morning.)

3.How often should it be used?

Once a week.

4.What happens if I forget to use the patch for a week?

Missing one application should not drastically affect results, but consistency is key. If you miss a week, it’s best to resume use as soon as possible.

5.Is it safe to use during pregnancy or breastfeeding?

As with any treatment, pregnant or breastfeeding women should consult their healthcare provider before using the patch to avoid any potential risks.

6.Can it be applied over a wound?

Please ensure the skin at the application site is cleaned before use, and avoid applying it to wounds, eczema, or other skin issues. If you experience any discomfort during use, discontinue immediately and consult a doctor.

7.Where should the patch be applied?

The microneedle patch should be applied to areas with good blood circulation, such as the upper arm or abdomen. If applied to areas with frequent joint movement, friction may cause it to detach or the needles to break.

8.Are there any side effects?

Common side effects could include minor irritation at the application site, redness, or slight itching. These usually resolve on their own. If you experience any severe reactions, it’s best to discontinue use and consult with a healthcare professional.

9.How should it be stored?

When unopened, the shelf life is 2 years. It should be stored at room temperature (20°C-25°C), avoiding moisture and high temperatures.

Product Specifications

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